Comparison of Injection Meglumine Antimoniate with a Combination of Injection Meglumine Antimoniate and Carbon Dioxide Fractional Ablative Laser in Treatment of Cutaneous Leshmaniasis

Aim: To see the efficacy of meglumine antimoniate alone in comparison with combination and CO2 ablative laser among patients cutaneous leishmaniasis. Study design: Quasi-experimental study. Place duration study: Department Dermatology, Pakistan Emirates Military Hospital, Rawalpindi from 9th July 2020 to 8th January 2021. Methodology: Sixty (30 each group) diagnosed cases leishmaniasis by skin biopsy or slit smear were enrolled. In group A; intramuscular injection (dose 20 mg/kg daily) was administered for 28 days B treated along fractional C02 laser. Standard digital photography done before start treatment then every 2 weeks. Results: Efficacy observed 60% while it 86.7% when combined Better outcome such both measured after 6 x weeks all groups. Clinical Implication: Hence lasers are latest modality minimal side effects can be used Conclusion: plus found higher as compared antimonate treating Keywords: Cutaneous leishmaniasis, laser, Meglumine antimoniate, Slit